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Carbidopa hydrochloride

CAT: 0931-T68937-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T68937-01Size:25 mg
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CAS Number
65132-60-7
Target
Others, Aryl Hydrocarbon Receptor
Related Pathways
Immunology/Inflammation, Others
Bioactivity
Carbidopa hydrochloride is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect.
Smiles
Cl.C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O
Molecular Formula
C10H15ClN2O4
Molecular Weight
262.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Carbidopa Hydrochloride

Carbidopa Hydrochloride is the hydrochloride salt form of carbidopa, a synthetic hydrazine derivative of the neurotransmitter dopamine. Carbidopa, a peripheral dopa decarboxylase inhibitor, is used as an adjunct with levodopa to prevent levodopa degradation to dopamine in extracerebral tissue, thereby decreasing the peripheral side effects of levodopa. Carbidopa does not penetrate the blood brain barrier; therefore, it does not interfere with the central nervous system (CNS) metabolism of levodopa to the active neurotransmitter dopamine which, in high concentrations in the brain, has anti-parkinsonian effects.

CAS Number65132-60-7
PubChem CID44152669
IUPAC Name(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid;hydrochloride
Molecular FormulaC10H15ClN2O4
Molecular Weight262.69
Topological Polar Surface Area116
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count17
Formal Charge0
Complexity261
SMILES
C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.Cl
InChI
InChI=1S/C10H14N2O4.ClH/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6;/h2-4,12-14H,5,11H2,1H3,(H,15,16);1H/t10-;/m0./s1
InChIKey
FRTJEAIOPNOZNI-PPHPATTJSA-N
Chemical Structure
2D Structure
2D structure of Carbidopa Hydrochloride
CAS: 65132-60-7
CID: 44152669
Formula: C10H15ClN2O4
MW: 262.69
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight262.69
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass262.0720347
Monoisotopic Mass262.0720347
Topological Polar Surface Area116 Ų
Heavy Atom Count17
Formal Charge0
Complexity261
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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