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Mafosfamide sodium

CAT: 0931-T68592-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T68592-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
84211-05-2
Target
Others
Related Pathways
Others
Bioactivity
Mafosfamide sodium is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide sodium alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, Mafosfamide sodium, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, Mafosfamide sodium is potentially useful in the intrathecal treatment of neoplastic meningitis.
Smiles
[Na+].[O-]S(=O)(=O)CCS[C@@H]1CCOP(=O)(N1)N(CCCl)CCCl
Molecular Formula
C9H18Cl2N2NaO5PS2
Molecular Weight
423.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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