Mafosfamide

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  Mafosfamide is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, mafosfamide, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, mafosfamide is potentially useful in the intrathecal treatment of neoplastic meningitis.

• Smiles :

  N(CCCl)(CCCl)P1(=O)N[C@H](SCCS(=O)(=O)O)CCO1

• Molecular Formula :

  C9H19Cl2N2O5PS2

• Molecular Weight :

  401.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  88859-04-5