Totrombopag choline

• Target :

  Others|||Thrombopoietin Receptor

• Related Pathways :

  Immunology/Inflammation|||Others

• Bioactivity :

  Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and potent agonist of the TPO receptor and therefore induces differentiation and proliferation of megakaryocytes. The pharmacologic characteristics indicate potential therapeutic use in thrombocytopenic patients with a variety of clinical etiologies.

• Smiles :

  C[N+](C)(C)CCO.CC1=NN(C(=O)C1N=Nc1cccc(-c2cccc(c2)-c2nnn[n-]2)c1O)c1ccc(C)c(C)c1

• Molecular Formula :

  C30H35N9O3

• Molecular Weight :

  569.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  851606-62-7