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(+/-) - Adomeglivant

CAT: 0931-T68471-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T68471-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
872260-47-4
Target
Others|||Endogenous Metabolite
Related Pathways
Others|||Metabolism
Bioactivity
(+/-) - Adomeglivant, also known as LY2409021, is a potent and selective glucagon receptor antagonist. LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes. Blockade of glucagon signalling in patients with type 2 diabetes is well tolerated and results in substantial reduction of fasting and postprandial glucose with minimal hypoglycaemia, but with reversible increases in aminotransferases. Inhibition of glucagon signalling by LY2409021 is a promising potential treatment for patients with type 2 diabetes and should be evaluated in longer clinical trials to better evaluate benefits and risks.
Smiles
CC1=C(C(C)=CC(OC(CCC(F)(F)F)C2=CC=C(C(NCCC(O)=O)=O)C=C2)=C1)C3=CC=C(C(C)(C)C)C=C3
Molecular Formula
C32H36F3NO4
Molecular Weight
555.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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