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Pirodomast

CAT: 0931-T67959-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T67959-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
108310-20-9
Target
Thrombin, Serine Protease, Leukotriene Receptor
Related Pathways
Proteases/Proteasome, GPCR/G Protein
Purity
>99.99%
Bioactivity
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospasm induced by histamine, methacholine, serotonin, LTC4, or platelet-activating factor. Pirodomast is a potential antiallergic compound. Pirodomast had only weak relaxant activity on guinea pig trachea in vitro. Pirodomast is a potential antiallergic compound that inhibits the protein hydrolyzing activity of trypsin in vitro, prevents antigen-induced immediate and late asthmatic responses in allergic sheep in vivo, and inhibits antigen-induced airway hyperresponsiveness to histamine and carbachol in allergic sheep.
Smiles
O=C1N(C=2C(C(=O)C1N3CCCC3)=CC=CN2)C4=CC=CC=C4
Molecular Formula
C18H17N3O2
Molecular Weight
307.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BUP11622-01Pirodomast

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