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Pirodomast

CAT: 1410-M36113-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M36113-01Size:1 Each
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Description
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospasm induced by histamine, methacholine, serotonin, LTC4, or platelet-activating factor. Pirodomast is a potential antiallergic compound. Pirodomast had only weak relaxant activity on guinea pig trachea in vitro. Pirodomast is a potential antiallergic compound that inhibits the protein hydrolyzing activity of trypsin in vitro, prevents antigen-induced immediate and late asthmatic responses in allergic sheep in vivo, and inhibits antigen-induced airway hyperresponsiveness to histamine and carbachol in allergic sheep.
CAS Number
108310-20-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
307.35
Molecular Formula
C18H17N3O2
Notes
Research use only, not for human use.
Receptor
Thrombin | Serine Protease

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