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JB061

CAT: 0931-T67951-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T67951-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Myosin
Related Pathways
Cytoskeletal Signaling
Purity
0.9967
Bioactivity
JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II) . It exhibits limited efficacy in reducing ATPase activity, with an IC50 exceeding 200 μM. Furthermore, JB061 displays cytotoxic effects on COS-7 cells, evidenced by an IC50 value of 39 μM.
Smiles
COc1cccc(C\N=C(/C)c2c(O)c3ccccc3oc2=O)c1
Molecular Formula
C19H17NO4
Molecular Weight
323.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
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CatalogName
BUP08222-01JB061

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