MCT1-IN-3

• Target:

  P-gp|||Monocarboxylate transporter

• Related Pathways:

  Membrane transporter/Ion channel|||Neuroscience

• Purity:

  0.9935

• Bioactivity:

  MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor, targeting solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) for cancer treatment. MCT1-IN-3 (compound 24) showed the highest MCT1 transport inhibition with an IC50 value of 81.0 Nm and also exhibits significant inhibitory activity against the multidrug transporter ABCB1.

• Smiles:

  C(=C(C(OC)=O)C#N)C=1C=2C(N(CC(NC3=CC=C(OC)C=C3)=O)C1)=CC=CC2

• Molecular Formula:

  C22H19N3O4

• Molecular Weight:

  389.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2878360-80-4