NBI-74330

• CAS Number :

  855527-92-3

• Target :

  CXCR

• Related Pathways :

  Autophagy|||Immunology/Inflammation|||GPCR/G Protein

• Purity :

  0.9937

• Bioactivity :

  NBI-74330 is a high-affinity CXCR3 antagonist that inhibits the binding of CXCR3 to its ligands CXCL10 and CXCL11, reduces the formation of atherosclerotic plaques in LDL receptor-deficient mice, and decreases the migration of CD4+ T cells and macrophages to the peritoneum.

• Smiles :

  [C@@H](N(CC=1C=CC=NC1)C(CC2=CC(C(F)(F)F)=C(F)C=C2)=O)(C)C=3N(C(=O)C=4C(N3)=NC=CC4)C5=CC=C(OCC)C=C5

• Molecular Formula :

  C32H27F4N5O3

• Molecular Weight :

  605.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C