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NBI-74330

CAT: 0931-T5644-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5644-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
855527-92-3
Target
CXCR
Related Pathways
Autophagy, Immunology/Inflammation, GPCR/G Protein
Purity
0.9937
Bioactivity
NBI-74330 is a high-affinity CXCR3 antagonist that inhibits the binding of CXCR3 to its ligands CXCL10 and CXCL11, reduces the formation of atherosclerotic plaques in LDL receptor-deficient mice, and decreases the migration of CD4+ T cells and macrophages to the peritoneum.
Smiles
[C@@H](N(CC=1C=CC=NC1)C(CC2=CC(C(F)(F)F)=C(F)C=C2)=O)(C)C=3N(C(=O)C=4C(N3)=NC=CC4)C5=CC=C(OCC)C=C5
Molecular Formula
C32H27F4N5O3
Molecular Weight
605.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A21158-50NBI-74330 50mg
A21158-100NBI-74330 100mg
A21158-10NBI-74330 10mg
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A21158-5NBI-74330 5mg
4528/10(±)-NBI 74330: 10 mg

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