NBI-74330

• Target:

  CXCR

• Related Pathways:

  Autophagy|||Immunology/Inflammation|||GPCR/G Protein

• Purity:

  0.9937

• Bioactivity:

  NBI-74330 is a high-affinity CXCR3 antagonist that inhibits the binding of CXCR3 to its ligands CXCL10 and CXCL11, reduces the formation of atherosclerotic plaques in LDL receptor-deficient mice, and decreases the migration of CD4+ T cells and macrophages to the peritoneum.

• Smiles:

  [C@@H] (N (CC=1C=CC=NC1) C (CC2=CC (C (F) (F) F) =C (F) C=C2) =O) (C) C=3N (C (=O) C=4C (N3) =NC=CC4) C5=CC=C (OCC) C=C5

• Molecular Formula:

  C32H27F4N5O3

• Molecular Weight:

  605.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  855527-92-3