Tetranor-PGAM

• Target:

  Others|||Drug Metabolite

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.

• Smiles:

  OC(=O)CCCCC(=O)CC[C@H]1C=CC(=O)[C@@H]1CCC(O)=O|c:12|

• Molecular Formula:

  C16H22O6

• Molecular Weight:

  310.346

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  52510-53-9