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SW2_110A acetate

CAT: 0931-T36798L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36798L-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
SW2_110A acetate is a selective, cell-permeable chromobox inhibitor of homologue CBX8 (Kd = 800 nM) bound to CBX8 N-terminal color gamut (ChD) . SW2_110A acetate has a high affinity for CBX8N, inhibits the association between CBX8 and cell chromatin, and inhibits the proliferation of ML-AF9-induced THP1 leukemia cells.
Smiles
CCN(CCCC[C@H](NC([C@H](NC([C@H](C1CCCC1)NC(C2=CC=C(OC3=CC=CC=C3)C=C2)=O)=O)[C@@H](C)CC)=O)C(N[C@@H](CO)C(NCC#C)=O)=O)CC.CC(O)=O
Molecular Formula
C44H64N6O9
Molecular Weight
821.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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