SB-265610

• Target:

  CXCR

• Related Pathways:

  GPCR/G Protein|||Autophagy|||Immunology/Inflammation

• Purity:

  0.995

• Bioactivity:

  SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1) -induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively) .

• Smiles:

  Brc1ccccc1NC (=O) Nc1ccc (C#N) c2nn[nH]c12

• Molecular Formula:

  C14H9BrN6O

• Molecular Weight:

  357.16

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  211096-49-0