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ABS-752

CAT: 0931-T212513-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212513-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2761170-84-5
Target
Molecular Glues, MAPK
Related Pathways
PROTAC, MAPK
Bioactivity
ABS-752 is an effective and orally active molecular glue degrader targeting GSPT1 and NEK7. It exhibits cytotoxic properties and reduces the protein expression of GSPT1, SALL4, and NEK7. ABS-752 possesses anticancer activity and shows potential for research in hepatocellular carcinoma.
Smiles
O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(C=C3C2)CN)CC1
Molecular Formula
C14H14FN3O3
Molecular Weight
291.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C