(GalNAc) 3-CPT

• Target:

  Phosphatase|||Apoptosis

• Related Pathways:

  Metabolism|||Apoptosis

• Bioactivity:

  (GalNAc) 3-CPT is a glycan-conjugated prodrug that targets the asialoglycoprotein receptor (ASGR) overexpressed on liver cells. It demonstrates significant antitumor activity by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumor sites, leading to apoptosis of tumor cells. In HepG2 cells, it shows an IC50 value of 3.07 ?M.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C