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(GalNAc) 3-CPT

CAT: 0931-T212503-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212503-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Phosphatase, Apoptosis
Related Pathways
Metabolism, Apoptosis
Bioactivity
(GalNAc) 3-CPT is a glycan-conjugated prodrug that targets the asialoglycoprotein receptor (ASGR) overexpressed on liver cells. It demonstrates significant antitumor activity by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumor sites, leading to apoptosis of tumor cells. In HepG2 cells, it shows an IC50 value of 3.07 μM.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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