Products for Research Use Only

HIV-1-IN-85

CAT: 0931-T212483-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212483-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Reverse Transcriptase, HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
HIV-1-IN-85 is an orally active HIV-1 inhibitor with an IC50 of 72 nM. It exhibits potent inhibitory activity against wild-type (WT) HIV-1 and single mutant strains resistant to non-nucleoside reverse transcriptase inhibitors (NNRTIs), such as L100I, K103N, Y181C, Y188L, and E138K. Additionally, it shows moderate inhibitory activity against double mutant strains (F227L+V106A, RES056) . In ICR mice, HIV-1-IN-85 demonstrates good in vivo safety and is suitable for research on HIV-1 infection.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C