K-833

• Target :

  GPCR

• Related Pathways :

  GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity :

  K-833 is a GPR119 agonist with EC50 values of 39.8 nM, 100 nM, 75.4 nM, and 12.6 nM for human, mouse, rat, and dog respectively. In acute intestinal peptide secretion in mice, K-833 modestly increases the secretion of glucagon-like peptide-1 (GLP-1) and, when used in combination with AM-5262, can synergistically enhance GLP-1 levels. K-833 is applicable in weight loss research.

• Smiles :

  C(CC1=C(F)C=C(OCCCC2CCN(CC2)C=3N=CC(Cl)=CN3)C=C1)(=O)N4CC(CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)C4

• Molecular Formula :

  C30H43ClFN5O7

• Molecular Weight :

  640.14

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2639936-77-7