Camptothecin derivative-3

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  Camptothecin derivative-3 (Compound 11) is a camptothecin derivative utilized as a payload for ADCs. It exhibits cytotoxic properties with IC50 values of 2 nM for HSC-2 and 0.9 nM for Namalwa/luc. Camptothecin derivative-3 is applicable in tumor-related research.

• Smiles :

  O=C1N2C(C=3C(C2)=C(CNC(CO)=O)C=4C(N3)=CC(F)=C(C)C4)=CC5=C1COC(=O)[C@@]5(CC)O

• Molecular Formula :

  C24H22FN3O6

• Molecular Weight :

  467.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2378619-11-3