2-ACC

• Target :

  Hedgehog/Smoothened

• Related Pathways :

  GPCR/G Protein|||Stem Cells

• Bioactivity :

  2-ACC (2-?-Carboxy cholestanol) is a cholestanol derivative that functions as an activator of the mutant Sonic Hedgehog protein D46A, with an EC50 of approximately 5 ?M.

• Smiles :

  C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC[C@]1(C[C@@H](O)[C@H](C(O)=O)C2)[H])[H])[H]

• Molecular Formula :

  C28H48O3

• Molecular Weight :

  432.68

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3091880-01-9