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AXT-914

CAT: 0931-T212185-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212185-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
717104-43-3
Target
SARS-CoV, CaSR
Related Pathways
Microbiology/Virology, GPCR/G Protein
Bioactivity
AXT-914 is an inhibitor of the calcium-sensing receptor (CaSR) . It exhibits antiviral activity against coronaviruses HCoV 229E and SARS-CoV2. AXT-914 reduces cytoplasmic calcium signaling activity caused by CaSR mutations. It is applicable in research on Bartter syndrome type 5, autosomal dominant hypocalcemia (ADH), and coronavirus infections.
Smiles
O=C1N=C(C=2C=CC(=CC2)C(C)C)C=3C=C(OCC#C)C=CC3N1CC4=CC=C(Br)C=C4
Molecular Formula
C27H23BrN2O2
Molecular Weight
487.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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