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UNC9750

CAT: 0931-T212123-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212123-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2967648-29-7
Target
PDGFR, Others, DAPK, DYRK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Cell Cycle/Checkpoint, Others
Bioactivity
UNC9750 is an inhibitor of inositol phosphate multikinase (IPMK), with IC50 values of 31.6 nM for IPMK and 374 nM for IP6K2. It effectively suppresses the accumulation of InsP5, a direct product of IPMK kinase activity, without affecting InsP6 or InsP7 levels. Additionally, UNC9750 inhibits over 75% of the activity of four kinases: DAPK1, DYRK1B, PDGFR, and KDR. This compound is applicable in glioblastoma research.
Smiles
N1=NNC(=N1)C=2C=CC3=NOC(C=4C=CC=C(C4)C5CCN(CC5)C6CCC6)=C3C2
Molecular Formula
C23H24N6O
Molecular Weight
400.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

(3P,5M)-3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(1H-tetrazol-5-yl)-2,1-benzoxazole
CAS Number2967648-29-7
PubChem CID170102738
IUPAC Name3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(2H-tetrazol-5-yl)-2,1-benzoxazole
Molecular FormulaC23H24N6O
Molecular Weight400.5
XLogP4.1
Topological Polar Surface Area83.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count30
Formal Charge0
Complexity580
SMILES
C1CC(C1)N2CCC(CC2)C3=CC=CC(=C3)C4=C5C=C(C=CC5=NO4)C6=NNN=N6
InChI
InChI=1S/C23H24N6O/c1-3-16(15-9-11-29(12-10-15)19-5-2-6-19)13-17(4-1)22-20-14-18(23-24-27-28-25-23)7-8-21(20)26-30-22/h1,3-4,7-8,13-15,19H,2,5-6,9-12H2,(H,24,25,27,28)
InChIKey
JZWSGCNSEOEUCD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (3P,5M)-3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(1H-tetrazol-5-yl)-2,1-benzoxazole
CAS: 2967648-29-7
CID: 170102738
Formula: C23H24N6O
MW: 400.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight400.5
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass400.20115941
Monoisotopic Mass400.20115941
Topological Polar Surface Area83.7 Ų
Heavy Atom Count30
Formal Charge0
Complexity580
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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