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XSJ81

CAT: 0931-T212076-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212076-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Bcl-2 Family, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Apoptosis
Bioactivity
XSJ81 is an orally active anticancer agent. It significantly inhibits the proliferation of ampullary cancer (AC) DPC-X3 cells, with an IC50 of 0.655 μM. XSJ81 suppresses colony formation and arrests the cell cycle at the G2/M phase while inhibiting cell migration. Additionally, XSJ81 induces DNA damage and apoptosis in DPC-X3 cells. In mouse models with DPC-X3 xenograft tumors, XSJ81 exhibits notable antitumor efficacy. This compound is applicable for research on ampullary cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-175589XSJ81

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