Chloroguanabenz acetate

• Target:

  Adrenergic Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  Chloroguanabenz (acetate) is an antiprion agent derived from guanabenz, an ?2-adrenergic receptor agonist. It inhibits prion formation in vitro in both yeast and mammalian models. Additionally, Chloroguanabenz (acetate) reduces levels of the truncated huntingtin protein derivative Htt48 in HEK293T cells and is used for studying Huntington's disease.

• Smiles:

  C(C)(O)=O.C(=N/NC(=N)N)\C1=C(Cl)C(Cl)=CC=C1Cl

• Molecular Formula:

  C10H11Cl3N4O2

• Molecular Weight:

  325.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2242615-97-8