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DDO-02267

CAT: 0931-T204967-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204967-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2919768-58-2
Target
ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
DDO-02267 is a selective lysine-targeted covalent inhibitor of ALKBH5, with an IC50 value of 0.49 μM. It increases levels of N6-methyladenosine (m6A) and targets the ALKBH5-AXL signaling axis. DDO-02267 serves as a probe for studying the biological function of mRNA demethylases.
Smiles
O=CC=1C=C(C=2C=CC=CC2C1O)S(=O)(=O)NC(=O)C3=NC=CC(=C3)C(=O)O
Molecular Formula
C18H12N2O7S
Molecular Weight
400.362
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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