CGRP antagonist 7

CAT: 0931-MF-0119017-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0119017-01Size:10 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2173508-07-9
Target
CGRP Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.
Smiles
C(CNC(=O)C1=CC(C)=C(CC=2C(=O)NN=C(C)C2)C=C1)(=O)N3[C@@H](CC[C@@H]3C(C#N)(C)C)C4=CC(F)=CC=C4
Molecular Formula
C30H32FN5O3
Molecular Weight
529.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products