CGRP antagonist 7

• Target:

  CGRP Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.

• Smiles:

  C (CNC (=O) C1=CC (C) =C (CC=2C (=O) NN=C (C) C2) C=C1) (=O) N3[C@@H] (CC[C@@H]3C (C#N) (C) C) C4=CC (F) =CC=C4

• Molecular Formula:

  C30H32FN5O3

• Molecular Weight:

  529.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2173508-07-9