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CGRP antagonist 7

CAT: 0931-T211975-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211975-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2173508-07-9
Target
CGRP Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.
Smiles
C(CNC(=O)C1=CC(C)=C(CC=2C(=O)NN=C(C)C2)C=C1)(=O)N3[C@@H](CC[C@@H]3C(C#N)(C)C)C4=CC(F)=CC=C4
Molecular Formula
C30H32FN5O3
Molecular Weight
529.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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