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CGRP antagonist 6

CAT: 0804-HY-162925Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162925Size:1 Each
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Description
CGRP antagonist 6 (Compound 23) is a CGRP receptor antagonist (Ki: 0.84 nM) . CGRP antagonist 6 can be used for research of migraine[1].
UNSPSC
12352211
Target
CGRP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgrp-antagonist-6.html
Smiles
O=C1[C@@H](NC(C2=CC=C3C(C[C@@]4(C(C=CC=N5)=C5NC4=O)C3)=C2)=O)C[C@@H](C6=CC=CC=C6)CN1CC(F)(F)F
Molecular Formula
C29H25F3N4O3
Molecular Weight
534.53
References & Citations
[1]Staas DD, et al. Invention of novel 3-aminopiperidin-2-ones as calcitonin gene-related peptide receptor antagonists. Bioorg Med Chem Lett. 2024 Nov 1;112:129944.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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