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VNRX-9945

CAT: 0931-T211971-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211971-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2396680-45-6
Target
HBV
Related Pathways
Microbiology/Virology
Bioactivity
VNRX-9945 is a potent and orally active HBV capsid assembly modulator (CAM), exhibiting an EC50 value of 2.6 nM. It demonstrates excellent and broad-spectrum antiviral activity against multiple HBV genotypes in vitro, with favorable pharmacokinetic properties across various species. Additionally, VNRX-9945 shows significant antiviral efficacy in the AAV-HBV infected mouse model.
Smiles
C(C(N[C@@H]1CC[C@H](O)CC1)=O)(=O)C2=C(C)C(C(NC3=CC(C)=C(F)C=C3)=O)=C(C)N2C
Molecular Formula
C23H28FN3O4
Molecular Weight
429.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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