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L14-8

CAT: 0931-T211601-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211601-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
MDM-2/p53, PLK, Ferroptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Bioactivity
L14-8 is a potent inducer of ferroptosis and facilitates the degradation of PLK1 through ubiquitination, while enhancing TP53 phosphorylation and SAT1 transcription, leading to ferroptosis and the death of cancer cells. L14-8 is applicable in studies of advanced prostate cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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