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(±) -Desisopropylpropranolol

CAT: 0931-T211546-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211546-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
20862-11-7
Target
Drug Metabolite, Adrenergic Receptor
Related Pathways
Neuroscience, Metabolism, GPCR/G Protein
Bioactivity
(±) -Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol. Propranolol acts as a non-selective β-adrenergic receptor (βAR) antagonist with high affinity for both β1AR and β2AR, having Ki values of 1.8 nM and 0.8 nM, respectively. It inhibits the binding of [3H]-DHA to rat brain membrane preparations with an IC50 of 12 nM. Propranolol is used in studies related to hypertension, pheochromocytoma, myocardial infarction, arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.
Smiles
OC(COC1=CC=CC=2C=CC=CC12)CN
Molecular Formula
C13H15NO2
Molecular Weight
217.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-W192276(±) -Desisopropylpropranolol
CSB-DT4901(S) -N-Desisopropylpropranolol
MBS9025384-01(S)-N-Desisopropylpropranolol

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