NADH-IN-3

• Target :

  Endogenous Metabolite

• Related Pathways :

  Metabolism

• Bioactivity :

  NADH-IN-3 (Compound C4-1) is an NADH inhibitor with a minimum inhibitory concentration (MIC) of 4 ?g/mL (13.042 ?M) against the type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb) . It effectively blocks ATP synthesis and demonstrates potent inhibitory effects on both single-drug (Rifampicin and Isoniazid) and multidrug-resistant (Mtb) strains, exhibiting antibacterial activity while maintaining low cytotoxicity towards HepG2 cells (SI: 16.52) .

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C