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KAT6A/KAT7-IN-1

CAT: 0931-T211266-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211266-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
KAT6A/KAT7-IN-1 (Example 113) is an inhibitor targeting both KAT6A and KAT7. It shows an IC50 for KAT6A of greater than 1 nM and up to 10 nM, while for KAT7, the IC50 is 1 nM or less. This compound suppresses acetylation of H3K14 and H3K23. Additionally, KAT6A/KAT7-IN-1 inhibits tumor cell proliferation with an IC50 for CAMA-1 of more than 2 μM but no greater than 5 μM. It is applicable in tumor research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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