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Vasoactive intestinal peptide

CAT: 0931-T211212-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211212-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
37221-79-7
Target
Interleukin, COX
Related Pathways
Neuroscience, Immunology/Inflammation
Bioactivity
Vasoactive intestinal peptide is an agonist of VPAC1/VPAC2 receptors (G protein-coupled receptors) . In a model of Pseudomonas aeruginosa-induced keratitis, it reduces corneal perforation rates, decreases bacterial load, and inhibits excessive neutrophil infiltration. It enhances anti-inflammatory mediators such as IL-10 and TGF-β while suppressing pro-inflammatory factors like IL-1β and TNF-α, and upregulates lipid mediator-related enzymes (SOCS3, COX-2, ALOX12) to facilitate inflammation resolution. Vasoactive intestinal peptide shows promise for the research of ocular infectious diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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