Products for Research Use Only

AF151

CAT: 0931-T211114-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211114-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, PROTACs, Bcl-2 Family, Others
Related Pathways
PROTAC, Apoptosis, Others
Bioactivity
AF151 is a METTL3 PROTAC degrader with a DC50 of 0.43 μM in MOLM-13 cells. It inhibits cell growth by significantly degrading METTL3 protein and reducing m6A levels. AF151 induces apoptosis and decreases Bcl-2 protein levels. This compound is applicable in research related to cancers such as acute myeloid leukemia (AML) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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