AF151

CAT: 0013-GTR19264168-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19264168-01Size:10 mg

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Description

AF151 is a METTL3 PROTAC degrader with a DC50 of 0.43 μM in MOLM-13 cells. It inhibits cell growth by significantly degrading METTL3 protein and reducing m6A levels. AF151 induces apoptosis and decreases Bcl-2 protein levels. This compound is applicable in research related to cancers such as acute myeloid leukemia (AML) .

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

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Alternative Products

Catalog	Name
HY-174873-01	AF151

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