SJL2-1

CAT: 0931-T211112-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T211112-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Dehydrogenase, Androgen Receptor, Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic, Endocrinology/Hormones, Metabolism

Bioactivity

SJL2-1 is a PRMT5 inhibitor with an IC50 value of 1.56 μM. It suppresses the proliferation, migration, and invasion of prostate cancer cells and induces apoptosis while causing cell cycle arrest at the G0/G1 phase. SJL2-1 targets intracellular PRMT5, inhibiting androgen receptor methylation and expression. It is applicable in research on early androgen-sensitive prostate cancer and advanced castration-resistant prostate cancer (CRPC) .

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-174908	SJL2-1
OF59775-01	1,1,1,1,1-Kestoheptaose
N2864-5.1	1,1,1,1-Kestohexaose
112040	1,1,1,1-Kestohexose
410417-01	1,1,1-Trichloromethanesulfonic Acid 1,1'-Anhydride
IFA69273-01	1-Iodobicyclo[1.1.1]pentane
OR312388	1-Phenylbicyclo[1.1.1]pentane
GTR19217879-01	AMPK-α1β1γ1 activator 1
OR300179	1-Isothiocyanatobicyclo[1.1.1]pentane

SJL2-1

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