SB-583355

CAT: 0931-T211104-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211104-01Size:10 mg
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CAS Number
3040121-49-8
Target
GPCR
Related Pathways
Endocrinology/Hormones|||GPCR/G Protein
Bioactivity
SB-583355 (Compound 56) is a potent G2A antagonist. It is synthesized through a Suzuki reaction of 4-methoxyphenylboronic acid with 3-bromo-4-hydroxybenzoic acid under specific conditions, followed by amide coupling. SB-583355 effectively blocks G2A activation mediated by 9-HOPE or T-10148 in CHO-K1 cells expressing human G2A. This compound is useful for investigating inflammation, myeloid leukemia, and neuropathic pain.
Smiles
OC=1C(=CC(C(N[C@@H](CC2=CC=CC=C2)C(NC3CCCCC3)=O)=O)=CC1)C4=CC=C(OC)C=C4
Molecular Formula
C29H32N2O4
Molecular Weight
472.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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