SB-583355

• Target:

  GPCR

• Related Pathways:

  Endocrinology/Hormones|||GPCR/G Protein

• Bioactivity:

  SB-583355 (Compound 56) is a potent G2A antagonist. It is synthesized through a Suzuki reaction of 4-methoxyphenylboronic acid with 3-bromo-4-hydroxybenzoic acid under specific conditions, followed by amide coupling. SB-583355 effectively blocks G2A activation mediated by 9-HOPE or T-10148 in CHO-K1 cells expressing human G2A. This compound is useful for investigating inflammation, myeloid leukemia, and neuropathic pain.

• Smiles:

  OC=1C (=CC (C (N[C@@H] (CC2=CC=CC=C2) C (NC3CCCCC3) =O) =O) =CC1) C4=CC=C (OC) C=C4

• Molecular Formula:

  C29H32N2O4

• Molecular Weight:

  472.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3040121-49-8