SB-583355

• CAS Number :

  3040121-49-8

• Target :

  GPCR

• Related Pathways :

  Endocrinology/Hormones|||GPCR/G Protein

• Bioactivity :

  SB-583355 (Compound 56) is a potent G2A antagonist. It is synthesized through a Suzuki reaction of 4-methoxyphenylboronic acid with 3-bromo-4-hydroxybenzoic acid under specific conditions, followed by amide coupling. SB-583355 effectively blocks G2A activation mediated by 9-HOPE or T-10148 in CHO-K1 cells expressing human G2A. This compound is useful for investigating inflammation, myeloid leukemia, and neuropathic pain.

• Smiles :

  OC=1C(=CC(C(N[C@@H](CC2=CC=CC=C2)C(NC3CCCCC3)=O)=O)=CC1)C4=CC=C(OC)C=C4

• Molecular Formula :

  C29H32N2O4

• Molecular Weight :

  472.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C