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GSK2220691

CAT: 0931-T211029-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211029-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1206619-37-5
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
SK2220691 is a potent TRPV4 inhibitor. It effectively suppresses pulmonary edema induced by GSK1016790. Additionally, SK2220691 inhibits the increase of crucial factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF) induced by hydrochloric acid.
Smiles
C([C@@H](NC(=O)C1=CC=2C(N1)=CC=CC2)[C@@](C)(C)C)(=O)N3[C@@]4(CN(C(=O)C5=CC=C(C=N5)C6=CC=CC=C6)[C@@](C4)(C3)[H])[H]
Molecular Formula
C32H33N5O3
Molecular Weight
535.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19263533-01GSK2220691

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