SGLT2-IN-2

CAT: 0931-T210997-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T210997-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Sodium Channel|||SGLT|||Autophagy
Related Pathways
GPCR/G Protein|||Others|||Membrane transporter/Ion channel|||Autophagy
Bioactivity
SGLT2-IN-2 (Compound E9) is an inhibitor of SGLT2 and significantly enhances the inhibition of SGLT2, NHE1, and SOD enzyme activities. It provides protection against myocardial cell damage induced by glucose-free DMEM. Additionally, SGLT2-IN-2 markedly improves cardiac function in TAC-induced heart failure (HF) mice, suppressing myocardial cell hypertrophy and collagen deposition. It reduces myocardial tissue damage and boosts autophagy in damaged myocardial cells, increasing the survival rate of HF mice.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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