SGLT2-IN-2

• Target:

  Others|||Sodium Channel|||SGLT|||Autophagy

• Related Pathways:

  GPCR/G Protein|||Others|||Membrane transporter/Ion channel|||Autophagy

• Bioactivity:

  SGLT2-IN-2 (Compound E9) is an inhibitor of SGLT2 and significantly enhances the inhibition of SGLT2, NHE1, and SOD enzyme activities. It provides protection against myocardial cell damage induced by glucose-free DMEM. Additionally, SGLT2-IN-2 markedly improves cardiac function in TAC-induced heart failure (HF) mice, suppressing myocardial cell hypertrophy and collagen deposition. It reduces myocardial tissue damage and boosts autophagy in damaged myocardial cells, increasing the survival rate of HF mice.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C