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Y040-7904

CAT: 0931-T210635-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210635-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PTEN, Mitophagy, Beta Amyloid
Related Pathways
PI3K/Akt/mTOR signaling, Neuroscience, Autophagy
Bioactivity
Y040-7904 is a potential mitochondrial autophagy activator. It enhances mitochondrial autophagy by facilitating the transport of mitochondria to autophagosomes and promoting the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitochondrial autophagy through the SIRT1/FoxO3 pathway and upregulates the levels of Parkin, PINK1, and LC3II/I. Additionally, Y040-7904 reduces Aβ accumulation in both in vitro and in vivo Alzheimer's disease models.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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