Y040-7904

• Target:

  PTEN|||Mitophagy|||Beta Amyloid

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Neuroscience|||Autophagy

• Bioactivity:

  Y040-7904 is a potential mitochondrial autophagy activator. It enhances mitochondrial autophagy by facilitating the transport of mitochondria to autophagosomes and promoting the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitochondrial autophagy through the SIRT1/FoxO3 pathway and upregulates the levels of Parkin, PINK1, and LC3II/I. Additionally, Y040-7904 reduces A? accumulation in both in vitro and in vivo Alzheimer's disease models.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C