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KMS99220

CAT: 0931-T210562-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210562-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1478585-60-2
Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
KMS99220 is an orally active Keap-1 activator that acts as an Nrf2 inhibitor protein. It enhances Nrf2 nuclear translocation, increases the expression of antioxidant enzymes (such as heme oxygenase-1) and proteasome subunit genes, and alleviates oxidative stress and protein aggregation damage. KMS99220 is applicable for research in Parkinson's disease (PD) .
Smiles
C(=C/C(=O)C1=CC=C(OCCCN2CCOCC2)C=C1)\C3=C(C(F)(F)F)C=CC=C3.Cl
Molecular Formula
C23H25ClF3NO3
Molecular Weight
455.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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