TYRA-200

• Target:

  FGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  TYRA-200 is an orally active FGFR1/2/3 inhibitor that induces dose-dependent tumor regression in wild-type and mutant FGFR2 models, making it a candidate for advanced or metastatic intrahepatic cholangiocarcinoma.

• Smiles:

  O=C(C=C)NC=1C=CC2=C(C1)C(=CN2C3=NC(=NC=C3F)NC=4C=NN(C4)CC(O)(C)C)C

• Molecular Formula:

  C23H24FN7O2

• Molecular Weight:

  449.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2823289-77-4