Products for Research Use Only

LTA4H-IN-5

CAT: 0931-T210386-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210386-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Aminopeptidase
Related Pathways
Metabolism
Bioactivity
LTA4H-IN-5 (Compound H122) is an orally active inhibitor of leukotriene A4 hydrolase (LTA4H), effectively suppressing both its aminopeptidase and hydrolase activities with IC50 values of 0.38 nM and 16.93 nM, respectively. In C57 mice, it demonstrates favorable pharmacokinetic properties and shows efficacy in improving DNBS-induced ulcerative colitis in rat models.
Molecular Formula
C18H17Cl2FN4O4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C