D-01

• Target :

  Histone Methyltransferase|||HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Metabolism|||Chromatin/Epigenetic

• Bioactivity :

  D-01 is a dual-target inhibitor of HIF-1? and EZH2, with IC50 values of 4.86 ?M and 0.99 ?M, respectively. It suppresses the expression of the H3K27me3 protein and inhibits the migration, colony formation, and invasion of A549 cells, as well as lumen formation in HUVEC. D-01 is applicable in lung cancer research.

• Molecular Formula :

  C37H43N3O8

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C