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(Rac) -Ketoconazole

CAT: 0931-T210027-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210027-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
79156-75-5
Target
Antifungal, Cytochromes P450
Related Pathways
Microbiology/Virology, Metabolism
Bioactivity
(Rac) -Ketoconazole ((Rac) -R 41400) is an orally active antifungal imidazole compound. It inhibits ergosterol synthesis in fungi by targeting the cytochrome P450-dependent enzyme, 14α-sterol demethylase (CYP51), on the fungal cell membrane. This disruption leads to dysfunction of the cell membrane, ultimately hindering fungal growth and proliferation. (Rac) -Ketoconazole is applicable in studying fungal infections.
Smiles
O=C(N1CCN(C2=CC=C(OCC3OC(OC3)(C4=CC=C(Cl)C=C4Cl)CN5C=NC=C5)C=C2)CC1)C
Molecular Formula
C26H28Cl2N4O4
Molecular Weight
531.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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