(Rac) -Ketoconazole

• CAS Number :

  79156-75-5

• Target :

  Antifungal|||Cytochromes P450

• Related Pathways :

  Microbiology/Virology|||Metabolism

• Bioactivity :

  (Rac) -Ketoconazole ((Rac) -R 41400) is an orally active antifungal imidazole compound. It inhibits ergosterol synthesis in fungi by targeting the cytochrome P450-dependent enzyme, 14?-sterol demethylase (CYP51), on the fungal cell membrane. This disruption leads to dysfunction of the cell membrane, ultimately hindering fungal growth and proliferation. (Rac) -Ketoconazole is applicable in studying fungal infections.

• Smiles :

  O=C(N1CCN(C2=CC=C(OCC3OC(OC3)(C4=CC=C(Cl)C=C4Cl)CN5C=NC=C5)C=C2)CC1)C

• Molecular Formula :

  C26H28Cl2N4O4

• Molecular Weight :

  531.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C