Products for Research Use Only

WS-384

CAT: 0931-T209577-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T209577-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2247544-03-0
Target
DNA/RNA Synthesis, Caspase, E1/E2/E3 Enzyme, Apoptosis, Histone Demethylase
Related Pathways
Apoptosis, Proteases/Proteasome, Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, Ubiquitination
Bioactivity
WS-384 is an orally active dual inhibitor of LSD1 and DCN1-UBC12 protein-protein interactions, with IC50 values of 338.79 nM and 14.81 nM, respectively. It exhibits anticancer properties, causing cell cycle arrest, DNA damage, and inducing apoptosis (apoptosis) . WS-384 can be applied in research on non-small cell lung cancer (NSCLC) .
Smiles
Cl.BrC1=CC=C(C=C1)CSC=2N=C3N=C(C=C(SC4=NN=NN4CCN(C)C)N3N2)C
Molecular Formula
C18H21BrClN9S2
Molecular Weight
542.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C