WS-384

• Target:

  DNA/RNA Synthesis|||Caspase|||E1/E2/E3 Enzyme|||Apoptosis|||Histone Demethylase

• Related Pathways:

  Apoptosis|||Proteases/Proteasome|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Ubiquitination

• Bioactivity:

  WS-384 is an orally active dual inhibitor of LSD1 and DCN1-UBC12 protein-protein interactions, with IC50 values of 338.79 nM and 14.81 nM, respectively. It exhibits anticancer properties, causing cell cycle arrest, DNA damage, and inducing apoptosis (apoptosis) . WS-384 can be applied in research on non-small cell lung cancer (NSCLC) .

• Smiles:

  Cl.BrC1=CC=C(C=C1)CSC=2N=C3N=C(C=C(SC4=NN=NN4CCN(C)C)N3N2)C

• Molecular Formula:

  C18H21BrClN9S2

• Molecular Weight:

  542.91

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2247544-03-0