SDX-7539

• Target:

  Aminopeptidase

• Related Pathways:

  Metabolism

• Bioactivity:

  SDX-7539 is a selective MetAP2 inhibitor that inhibits the proliferation of HUVEC, with an IC50 of 120 ?M. It has demonstrated antitumor activity in xenografted NSCLC in athymic nude mice.

• Smiles:

  C[C@@]1([C@@]2([C@@]3(CO3)CC[C@@H](OC(N[C@@H]4CC[C@@H](N)CC4)=O)[C@H]2OC)[H])[C@@H](CC=C(C)C)O1

• Molecular Formula:

  C23H38N2O5

• Molecular Weight:

  422.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1631953-52-0