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SARS-CoV-2-IN-77

CAT: 0931-T209180-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209180-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Cysteine Protease, SARS-CoV
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
SARS-CoV-2-IN-77 (compound 11e) is an inhibitor of cathepsin L and cathepsin S, with Ki values of 111 nM and 103 nM, respectively. It effectively inhibits SARS-CoV-2 in Calu-3 cells with an EC50 value of 38.4 nM and does not exhibit cytotoxicity.
Molecular Formula
C23H25Cl2N3O3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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