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BiKEAP1

CAT: 0931-T209107-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209107-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
BiKEAP1 (compound 3) is an inhibitor that targets the KEAP1 dimer. By binding to cellular KEAP1 dimers, biKEAP1 releases the NRF2 protein that is sequestered by KEAP1, leading to the immediate activation of NRF2. This compound also promotes the nuclear translocation of NRF2 and directly inhibits the transcription of pro-inflammatory cytokines. biKEAP1 has demonstrated the ability to alleviate acute inflammation and reduce inflammatory damage in acute inflammation models.
Molecular Formula
C61H60N8O18S4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-162152-01BiKEAP1

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