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BET-IN-21

CAT: 0931-T208765-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208765-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3014815-06-3
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
BET-IN-21 (compound 16) is a BET (Bromo and Extra-Terminal domain) inhibitor capable of penetrating the blood-brain barrier, with a Ki value of 230 nM. It suppresses microglial activation and demonstrates therapeutic effects in mice with experimental autoimmune encephalomyelitis.
Smiles
N=1C=C(C=C(C1)C=2C(=NN(C2C)CC3CC3)C)C4=CC=NC=5N=CNC54
Molecular Formula
C20H20N6
Molecular Weight
344.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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