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(R) -Acenocoumarol

CAT: 0931-T208711-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208711-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
66556-77-2
Target
Vitamin
Related Pathways
Metabolism
Bioactivity
(R) -Acenocoumarol ((R) -Acenocoumarin; (R) -Nicoumalone) is a short-acting, orally administered anticoagulant that works by inhibiting vitamin K epoxide reductase (vitamin K1 recycling), similar to Warfarin. It demonstrates greater anticoagulant potency in vivo compared to Warfarin. This compound has a single chiral center, resulting in two enantiomeric forms. The (R) -enantiomer has a longer plasma elimination half-life of 6.6 hours, slower plasma clearance of 1.9 L/h, and stronger anticoagulation effects than the (S) -enantiomer.
Smiles
CC(C[C@H](C1=CC=C(C=C1)[N+]([O-])=O)C2=C(C3=CC=CC=C3OC2=O)O)=O
Molecular Formula
C19H15NO6
Molecular Weight
353.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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